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Pathology Cellular Pathology 04f76805

Ladder pattern of DNA electrophoresis is seen in

A
Necrosis
B
Apoptosis
C
Cytolysis
D
Karyorrhexis
High-Yield Explanation
Ans. (b) Apoptosis(Ref: Robbins 9th/pg 53; R 9th/pg 29-30)DNA breakdown (Internucleosome cleavage by endonuclease into 200 bp oligonucleosomes is a characteristic)Q at specific sites can be detected by 'step ladder pattern' on gel electrophoresis or TUNEL (TdT mediated d-UTP Nick End Labelling) technique

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