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Pharmacology General 04c68db8

Imipenem, a newer antibiotic with a broad antibacterial spectrum, is co administered with cilastatin. Which of the following is the best reason for the same?

A
Combination of antibiotics is synergistic against Pseudomonas specie
B
Cilastatin aids gastrointestinal absorption of active moiety, imipenem
C
Cilastatin inhibits beta=lactamase enzyme destroying imipenem
D
Cilastatin inhibits an enzyme in kidney destroying imipenem
High-Yield Explanation
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