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Medicine Liver 04b4d047

A 15 year old child has developed dystonia and poor school grades. Slit examination is shown below. Which is the initial investigation recommended for the patient ?

A
Serum ceruloplasmin
B
Serum copper
C
24 hour urinary copper
D
Liver biopsy
High-Yield Explanation
KF Ring can be seen in the image which is seen in Wilson disease Screening test:- 24 hours urinary copper Conformational:- Biopsy. Rx: Trientine- copper chelator Penicillamine- also chelator but less used due to nephrotic side effect. Zinc- is competitive inhibitor of copper in absorption of gut. Zinc acetateisDOCfor Wilson disease.

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