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Biochemistry General 048d5f1c

Which of the following liver enzymes is predominantly mitochondrial

A
SGOT (AST)
B
SGPT (ALT)
C
GGT
D
5' Nucleotidase
High-Yield Explanation
Liver enzymes location Ectoenzymes (Plasma membrane-bound) :- 5' nucleotidase (also called nucleotide phosphatase, NTP), Gamma-glutamyl transferase (gamma-glutamyl transpeptidase : GGT), alkaline phosphatase (ALP). Mitochondrial:- Glutamate dehydrogenase (GDH), Aspartate aminotransferase (AST) or SGOT mitochondrial isoenzyme. Cytosolic:- Lactate dehydrogenase (LDH), Alanine transaminase (ALT) or SGPT, SGOT (AST) cytosolic isoenzyme. Note:- In liver, the predominant isoenzyme of SGOT (AST) is mitochondrial.

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