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Biochemistry All India exam 04794897

Protein di sulphide isomerase is involved in

A
Protein synthesis
B
Protein degradation
C
Protein folding
D
Protein quaernary structure formation
High-Yield Explanation
Disulfide bonds between and within polypeptides stabilize teiary and quaternary structures. However, disulfide bond formation is nonspecific. Under oxidizing conditions, a given cysteine can form a disulfide bond with the --SH of any accessible cysteinyl residue. By catalyzing disulfide exchange, the rupture of an S--S bond and its reformation with a different paner cysteine, protein disulfide isomerase facilitates the formation of disulfide bonds that stabilize a protein&;s native conformationPeptidyl cis-trans isomerase, protein disulphide isomerase and chaperones are involved in protein folding

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