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Medicine G.I.T 0477f614

30 year male with chronic diarrhoea, anemis, raised liver enzymes. Most likely associated with-

A
Antimitochondrial antibody
B
Anti-endomysial antibody
C
Anti-smooth muscle antibody
D
Antinuclear antibody
High-Yield Explanation
IgA anti-endomysial antibodies are found in 90% coeliac patients. They are a very specific & sensitive marker for coeliac disease and dermatitis herpetiformis. The anti-endomysial antibody test has been suggested to be 98% sensitive and 98% specific for clinical or subclinical coeliac disease Ref Davidson edition23rd pg 805

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