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Pathology AIIMS 2019 0447b9a2

Which of the following finding are there in iron deficiency anemia?

A
| TIBC, | Ferritin, | Transferrin saturation
B
| TIBC, | Ferritin, | Transferrin saturation
C
| TIBC, | Ferritin, | Transferrin saturation
D
| TIBC, | Ferritin, | Transferrin saturation
High-Yield Explanation
The diagnosis of iron deficiency anemia ultimately rests on laboratory studies. The serum iron and ferritin are low, and the total plasma iron-binding capacity (reflecting elevated transferrin levels) is high. Low serum iron with increased ironbinding capacity results in a reduction of transferrin saturation to below 15%. Reduced iron stores inhibit hepcidin synthesis, and its serum levels fall.

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