A 50 year old male is taking medication for tuberculosis since the last 2 months comes to the OPD with a complaint of hearing problems. The drug with which of the following mechanisms of action is most likely causing these symptoms?
High-Yield Explanation
Streptomycin used in Tuberculosis produce ototoxicity. Aminoglycosides act by inhibiting protein synthesis after binding to the 30s ribosome and inhibiting 1st step - initiation complex formation.Ref: Katzung 13th ed Pg 799