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Pathology General 0418a3c6

A married middle aged female gives history of repeated aboions for the past 5 years. The given below is conceptions pre-natal karyogram. This karyogram suggests the following -

A
Klinefelter's syndrome
B
Turner's syndrome
C
Down's syndrome
D
Patau's syndrome
High-Yield Explanation
Ans. is 'c' i.e., Down's syndrome Most common chromosomal abnormalies causing aboion are chromosomal trisomy. Trisomy 21 is synonymous with down's syndrome and is the most common of the chromosomal disorders Trisomy 21 DOWN SYNDROME Trisomy 18 EDWARD SYNDROME Trisomy 13 PATAU SYNDROME

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