In which of the following types of Carcinoma Breast, Comedo growth pattern in seen?
High-Yield Explanation
Historically, ductal carcinoma in situ (intraductal carcinoma) has been divided into five architectural subtypes: comedocarcinoma, solid, cribriform, papillary and micropapillary. Comedocarcinoma is characterized by solid sheets of pleomorphic cells with high-grade nuclei and central necrosisThe necrotic cell membranes commonly calcify and are detected on mammography as clusters of linear and branching microcalcifications.