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Pathology General 03e40377

Salt losing nephritis is a feature of-

A
Interstitial nephritis
B
Polycystic kidney
C
Lupus nephritis
D
Renal amyloidosis
High-Yield Explanation
Ans. is 'a' i.e., Interstitial nephritisCAUSES OF TUBULOINTERSTITIAL DISEASESInfectionso Acute bacterial pyelonephritiso Chronic pyelonephritis (including reflux nephropathy)o Other infections (e.g. viruses, parasites) Toxinso Drugso Acute hypersensitivity interstitial nephritis o Analgesic nephropathyo Heavy metalso Lead, cadmiumMetabolic diseaseso Urate nephropathyo Nephrocalcinosiso Hypokalemic nephropathyo Oxalate nephropathyPhysical factorsChronic urinary tract obstructionRadiation nephropathy NeoplasmsMultiple myelomaImmunological reactionsTransplant rejectionSjogren syndromeSarcoidosisVascular diseasesMiscellaneousBalkan nephropathyNephronopthsis - medullary cystic disease complexIdiopathic interstitial nephritisFollowing information have been added in 8th/e of Robbins Aristolochic nephropathyo A syndrome of tubulointerstitial nephritis caused by aristolochic acid, a supplement found in some herbal remedies, has been recognized recently.o The drug forms covalent adducts with DNA and causes a distinctive picture of renal failure and interstitial fibrosis associated with a relative paucity of infiltrating leukocytes.o There is an increased incidence of carcinoma in the kidney and urinary tract.

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