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Biochemistry Molecular Genetics 03bfd74c

Which of the following blotting technique does not exist:

A
Western
B
Southern
C
Eastern
D
Northern
High-Yield Explanation
Ans: c (Eastern) Ref: Lippincott, p. 464Few points about gene analysis:TechniqueSample analysedPurposeASO (Allele specific oligonucleotide)DNADetects DNA mutationsMicro assayRNA or C-DNAMeasures many mRNA levels at onceProteonomicsProteinMeasures abundance, distribution, post translational modification, functions and interactions of cellular proteinsDNA chipsDNAOligonucleotides embedded on the chip can detect various DNA mutations and diseasesNumerical chromosomal abnormalities:Euploid cells: Multiples of 23 chromosomes.E.g.: Haploid (23). dipoid (46), triploidetc.Aneuploidy: Deviation from euploid number.E.g.: Trisomy - Three copies of a specific chromosome.Monosomy - One copy of a specific chromosome.Nullysomy - No copy of a specific chromosome.

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