Pathology Bleeding Disorders 039f5c62

Factor Xa is necessary for conversion of prothrombin to thrombin

Only in the extrinsic pathway

Only in the intrinsic pathway

As part of both extrinsic and intrinsic pathways

Only if the normal blood clotting cascade is inhibited

High-Yield Explanation

Ans. (c) As part of both extrinsic and intrinsic pathways(Ref: Robbins 9th/pg 118-119; 8th/pg 119)Activated factor IX along with factor VIIIa (Intrinsic pathway) & factor VIIa (extrinsic pathway), converge to activate Factor X to Xa is necessary for conversion of prothrombin to thrombin (common pathway)

Factor Xa is necessary for conversion of prothrombin to thrombin

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