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Gynaecology & Obstetrics Cervical Carcinoma 0396fe06

A cervical Pap smear repo stating that "koilocytic atypia is present" indicates the:-

A
Presence of high-grade cervical intraepithelial neoplasia
B
Cytologic effect of herpesvirus type 2
C
Cytologic effect of human papillomavirus
D
Presence of chlamydial infection
High-Yield Explanation
HPV infection of squamous cells Produces wrinkled nuclei surrounded by a clear halo. This is called koilocytosis. Whether it is indicative of a low or a high grade lesion in the cervix requires tissue documentation. This is usually obtained with a colposcopic biopsy.

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