Pharmacology General 03898aea Local anaesthetics act by inhibiting - A Influx of K+ B Efflux of K+ C Influx of Na+ D Efflux of Na+ High-Yield Explanation Ans. is 'c' i.e., Influx of Na+ The LAs block nerve conduction by decreasing the entry (influx) of Na+ ions during upstroke of action potential.