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Pharmacology General 0354a7ab

Which of the following statement is false regarding mebendazole?

A
Safe in pregnancy
B
Broad spectrum antihelmenthic
C
It is effective against egg and adults
D
It act on cytoplasmic microtubules
High-Yield Explanation
Mebendazole is a benzimidazole derivative with antihelmintic effect. It causes degeneration of parasite's cytoplasmic microtubules and thereby selectively and irreversibly blocks glucose uptake in susceptible adult intestine-dwelling helminths and their tissue-dwelling larvae. Mebendazole has shown embryotoxic and teratogenic activity. It's contraindicated in pregnancy as with the case albendazole.

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