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Biochemistry Vitamins 0343ea4a

Which coenzyme is responsible for carboxylation reaction?

A
Biotin
B
FAD
C
NADH
D
Thiamine pyrophosphate
High-Yield Explanation
Ans. is 'a' i.e. biotin Biotin is the coenzyme required for enzymes that are involved in carboxylation reactions, e.g. acetyl-CoA carboxylase and pyruvate carboxylase.* Most coenzymes are derived from vitamins. Below is given list of vitamins, derived coenzymes and the reactions they are involved in: VitaminCoenzymeReaction typeBi (Thiamine)TPP (thiamine pyrophosphate)Oxidative decarboxylation, transketolationB2 (Riboflavin)FMN, FADOxidation/ReductionB3(Pantothenate)CoA-Coenzyme AAcyl group transferB6 (Pyridoxine)PLP (Pyridoxal phosphate)Transfer of groups to and from amino acids (Transamination,Deamination, Condensation, Decarboxylation)Bj2 (Cobalamin)5-deoxyadenosyl cobalamin,methylcobalaminIsomerization of methylmalonyl, synthesis of mehionineNiacinNAD+, NADP+Oxidation/ReductionFolic acidTetrahydrofolateOne carbon group transferBiotinBiotinCarboxylationVitamin KVitamin KCarboxylation of glutamic acid residues

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