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Pediatrics General 02b4aede

Which of the following malformation in a newborn is specific for maternal insulin dependent diabetes mellitus ?

A
Transposition of great arteries
B
Caudal regression
C
Holoprosencephaly
D
Meningmyelocele
High-Yield Explanation
The fetal malformations seen in Caudal regression syndrome are the most typical seen in cases of maternal diabetes'.- Early detection of caudal regression syndrome, D. Subtil et al. Caudal regression : Caudal regression syndrome (CRS) is a rare malfonnative syndrome seen mainly in cases of maternal diabetes with poor metabolic control. This syndrome associates vertebral agenesis of variable level with genito-urinary and digestive malformations. These abnormalities are related to the impaired development of the mid-posterior axis mesoderm

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