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Medicine Lymphoma 02adc917

The paraneoplastic syndrome associated with Hodgkin's disease is -

A
Nephrotic syndrome
B
Retinopathy
C
Cerebellar degenerative disease
D
Acanthosis nigricans
High-Yield Explanation
Ans. is 'c' i.e., Cerebellar degenerative disease CNS Paraneoplastic syndromes:SyndromeTargetTumour* Subacute cerebellar degenerationPurkinje cellHodgkin lymphoma, Breast, Ovary, Small cell Ca lung, Neuroblastoma* Limbic encephalitisVarious neuronsSCLC, Neuroblastoma* Brainstem encephalitisIn mesial temporal lobe, brainstemTesticular, others* Subacute sensoryDorsal root ganglionSCLC,neuropathyneuronNeuroblastoma* Opsoclonus myoclonusUnknown (presumed brain stem)Neuroblastoma,Breast* Retinal degenerationPhotoreceptorsSCLC* Stiff-man syndromeSpinal interneuronBreast* Lambert-Eaton myasthenic syndromePresynaptic terminals at neuromuscular junctionSCLC

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