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Pharmacology Opioids 02906c96

Which of the following is TRUE for morphine :

A
Tolerance to all its actions except sedation and euphoria
B
Tolerance to all side effects except constipation and miosis.
C
It is a peripherally acting analgesic.
D
It has no abuse potential.
High-Yield Explanation
Ans. is 'b' Tolerance to all its action except constipation and miosis Tolerance is exhibited to most actions of morphine except for miosis and constipation. Morphine is a centrally acting analgesic. It has site-specific depressant and stimulant action in CNS. Morphine produces pronounce psychological and physical dependence, its abuse liability is very high. Withdrawal of morphine is associated with marked drug seeking behaviour. These are: Lacrimation* Mydriasis * Sweating Diarrhoea* Insomnia* Tremor Rise in B.P.

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