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Pathology General pathology 028e39af

In genetic deficiency of MPO the increased susceptibility to infection is due to -

A
Defective production of Prostaglandins
B
Defective rolling of neutrophils
C
Inability to produce hydroxyl-halide radicals
D
Inability to produce hydrogen peroxide
High-Yield Explanation
Myeloperoxidase is an enzyme in Macrophages for production of hypochlorous radical from H2O2, which kills bacteria. Basic Pathology, Robbins. Page no.: 38

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