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Radiology Radiotherapy 028bbe8c

The thresholds for permanent sterility in women for prepubeal exposure and premenopausal exposure conditions are

A
1 Gy and 0.2 Gy, respectively
B
6 Gy and 2 Gy, respectively
C
12 Gy and 2 Gy, respectively
D
0.5 to 2 Gy and 20 Gy, respectively
High-Yield Explanation
In women, radiation is highly effective at inducing permanent ovarian failure, but there is a marked age dependence insensitivity. The dose required to induce permanent sterility varies from 12 Gy (1,200 rad) prepubeal to 2 Gy (200 rad) premenopausal. Pronounced hormonal changes, comparable to those associated with the natural menopause, accompany radiation-induced sterilization in females.Reference: Eric J Hall Textbook of Radiobiology for Radiologist; 5th edition

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