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Pharmacology Endocrinology 026fc016

Antithyroid drug of choice in pregnancy -

A
Carbimazole
B
Iodine therapy
C
Propylthiouracil
D
Metimazole
High-Yield Explanation
Ans. is 'c' i.e., Propylthiouracil o Both carbimazole and propylthiourcil can be used during pregnancy, but propyl-thiouracil is the drug of choicebecause its greater protein binding allows low doses of propylthioracil to be transferred across the placenta and therefore less chance of hypothyroidism.

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