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Biochemistry Respiratory chain 02240787

Barbiturates act on which step of mitochondrial respiratory chain?

A
Compelx 1 to co-enzyme Q
B
Compelx 2 to co-enzyme Q
C
Co-enzyme Q to compelx 3
D
Cytochrome C to compelx 4
High-Yield Explanation
1. Complex I to Co-Q specific inhibitorsAlkylguanides (guanethidine), hypotensive drugRotenone, insecticide and fish poisonBarbiturates (amobarbital), sedativeChlorpromazine, tranquilizerPiericidin, antibioticRef: DM Vasudevan Textbook of Medical Biochemistry, 6th edition, page no: 234

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