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Pharmacology General 0217d0a4

Antidepressant causing Tardive dyskinesia is ?

A
MAO inhibitors
B
Mianserin
C
Imipramine
D
Amoxapine
High-Yield Explanation
Ans. is 'd' i.e., Amoxapine Amoxapine is the only antidepressant which blocks D2 receptors along with inhibition of NA reuptake - has mixed antidepressant + neurolepic propey. Due to blockade of D, receptors it causes extrapyramidal side effects -4 Parkinsonism, Tardive dyskinesia, Akathesia, neuropeptic malignant syndrome.

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