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Pharmacology General 02045e18

Neurological transmission is affected by ?

A
Sulfonamides
B
Nitrofurantoin
C
INH
D
Streptomycin
High-Yield Explanation
Ans. is 'd' i.e., Streptomycin o All aminoglycosides reduce Ach release from the motor nerve endings. They interfere with mobilization of centrally located synaptic vesicles to fuse with the terminal membrane (probably by antagonizing Ca2+) as well as decrease the sensitivity of the muscle end plates to Ach.

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