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Pediatrics Disorders of the Respiratory Tract 01f0fead

Omalizumab True statement is-

A
Anti-IgE
B
Used as add on therapy in moderate to severe asthma prophylaxis
C
Givn subcutaneously
D
All o above
High-Yield Explanation
Ans. is 'd' i.e.* All of above Anti-IgE (Omalizumab).o Omalizumab is a humanized monoclonal antibody that binds IgE, thereby presenting its binding to the high- affinity IgE receptor and blocking IgE-mediated allergic responses and inflammation,o approved for patients >12 yr old with moderate to severe asthma,o It is given even' 2-4 wk subcutaneously based on body weight and serum IgE levels.o Its clinical efficacy-> as an "add-on " therapy for patients with moderate to severe allergic asthma It is generally well tolerated, although local injection site reactions can occur.

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