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Pediatrics Genetics And Genetic Disorders 01bfa529

Most common enzyme deficiency among these which leads to childhood hypertension:

A
21 hydroxylase deficiency
B
11-beta hydroxylase deficiency
C
3-beta hydroxysteroid dehydrogenase deficiency
D
17-alpha hydroxylase deficiency
High-Yield Explanation
Ans. B. 11-beta hydroxylase deficiencyChildhood hypertension and salt retention are seen in children with 11-beta hydroxylase deficiency and 17-alpha hydroxylase deficiency. The second most common cause of CAH (after 21 hydroxylase deficiency) is 11-beta hydroxylase deficiency.

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