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Pediatrics General 0149ede1

All of the following conditions are observed in Marasmus, except –

A
Hepatomegaly
B
Muscle wasting
C
Low insulin levels
D
Extreme weakness
High-Yield Explanation
Changes in body composition in P.E.M. Fluid considerations- Total body water in malnourished children is increased to 70-80% of body weight as compared to 60% in age-matched well-nourished controls. The activity of the sodium pump* is reduced. Metabolic alterations. B.M.R. is reduced by 30% and energy expenditure due to inactivity is very low The child may behave like poikilotherm. Endocrine changes. Insulin levels are reduced (child has glucose intolerance) Cortisol and growth hormone levels are increased. Cardiovascular system Cardiac output and stroke volume are reduced Blood pressure is low and renal perfusion is compromised. Renal function Glomerular filtration rate and renal plasma flow are reduced in severe P.E.M. Urinary phosphate and sodium excretion are reduced.

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