Tau protein seen in -

Ans. is 'a' i.e., Alzheimer's disease Alzhiemers diseaseo There is atrophy of frontal and temporal lobes to variable extent and severity,o The pattern of atrophy can often be predicted in part by the clinical symptomatology.o The atrophic regions of cortex are marked by neuronal loss, gliosis, and the presence of tan-con taining neurofibrillary tangles