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Microbiology Bacteria 0105e842

A diabetic patient developed cellulite is due to S. aureus, which was found to be methicillin resistant on the antibiotic sensitivity testing. All of the following antibiotics will be appropriate except:

A
Vancomycin
B
Imipenem
C
Teicoplanin
D
Linezolid
High-Yield Explanation
Ans. is 'b' i.e., Imipenem(Ref: Harrison, 18th/e, p. 1168 and 17th/e, p. 879)"The carbapenem imipenem has excellent activity against methicillin - sensitive S. aureus but not M.R.S.A." Because MRSA is resistant to all Beta-lactam antibiotics including cephalosporins and carbapenems.

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