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Pharmacology General 00e8a051

NOT of use in bipolar disorder: September 2012

A
Carbamazepine
B
Phenytoin
C
Sodium valproate
D
Lamotrigine
High-Yield Explanation
B i.e. Phenytoin Phenytoin It acts to suppress the abnormal brain activity seen in seizure by reducing electrical conductance among brain cells by stabilizing the inactive state of voltage-gated sodium channels. Aside from seizures, it is an option in the treatment of trigeminal neuralgia in the event that carbamazepine or other first-line treatment seems inappropriate. It is sometimes considered a class lb antiarrhythmic.

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