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Surgery General 009c363a

All of the following are true about fibrolamellar carcinoma of the liver except:

A
More common in females
B
Better prognosis than HCC
C
AFP levels always greater than 1000
D
Occur in younger individuals
High-Yield Explanation
It is AFP-negative, but patients typically have elevated neurotensin levels, normal liver function tests, and no cirrhosis. Ref: Harrison's Internal Medicine, 14th Edition, Page 580, 15th Edition, Page 590 and 18th Edition, Pages 784-785; Concise Pathology, 2nd Edition By Para Chandrasoma, Clive Roy Taylor, Page 650.

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