Which of the following are morphological features of childhood polycystic kidney disease?
High-Yield Explanation
Autosomal recessive polycystic kidney disease (ARPKD)/Childhood polycystic kidney disease Kidneys - Enlarged, smooth external appearance. Cut section, numerous small cysts give kidney a "sponge-like" appearance. Dilated elongated channels are present at right angles to the coical surface, completely replacing the medulla and coex. M/E - Cylindrical or, less commonly, saccular dilation of all collecting tubules. The cysts have a uniform lining of cuboidal cells.