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Pathology Uterus 002b10de

On routine examination, it is discovered that a 35-year-old woman had been exposed in-utero to Diethylstilbestrol (DES) administered to her mother, who had had a history of recurrent spontaneous aboion. This history suggests that the patient might be at increased risk of which of the following?

A
Adenomyosis
B
Clear cell adenocarcinoma
C
Lichen sclerosus
D
Squamous cell carcinoma
High-Yield Explanation
Diethylstilbestrol (DES) is the risk factor for clear cell adenocarcinoma of the vagina and cervix in young women with a history of in utero exposure to DES while their mothers were pregnant.

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