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Pathology General 00178a32

Which of the following is a ourable prognostic factor in a case of neuroblastoma?

A
Diploidy
B
N-myc amplification
C
Chromosome / p depletion
D
Trk A expression
High-Yield Explanation
High level expression of Trk A gene is associated with a ourable outcome in neuroblastoma. Favorable prognostic factors in neuroblastoma are: Age less than 1 year, Stage I and II, hyperdiploid or near diploid tumors. Ref: Robbins Pathologic Basis of Disease, 6th Edition, Page 485, 487

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