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Microbiology General 000cdb28

EBV (epstein barr virus) causes all except: September 2005 & March 2013

A
Glandular fever
B
Burkitt's lymphoma
C
Pancreatic carcinoma
D
Nasopharyngeal carcinoma
High-Yield Explanation
Ans. C: Pancreatic carcinoma Epstein-Barr virus (EBV) causes infectious mononucleosis as a primary disease. The virus infects more than 90% of the average population and persists lifelong in peripheral B-lymphocytes. The virus is produced in the parotid gland and spread the oral route. Serology suggests that the Epstein-Barr virus might be involved in the causation of two neoplastic diseases of humans: African Burkitt's lymphoma and nasopharyngeal carcinoma. Whereas the development of the lymphoma has an even better linkage with chromosomal rearrangements, nasopharyngeal carcinoma shows a unique association with Epstein-Barr virus It is also associated with causation of glandular fever and lymphoma

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